Helicobacter pylori should be eradicated in patients receiving long-term acid suppression

摘要: Twenty years after the first culture of Helicobacter pylori, association this bacterium with a variety closely related upper gastrointestinal disorders, such as chronic gastritis and peptic ulcer disease, has become clearly established. This necessitated development effective eradication therapies. Once these therapies became available, indications for H. pylori therapy have gradually expanded, but international guidelines on still show major differences, in fact agree only indication that should be eradicated patients disease1–7. Controversies remain various issues need non-ulcer dyspepsia, NSAID users, who are treated profound acid suppression. The latter is very disorders mainstay treatment gastro-oesophageal reflux disease (GORD). reason to consider suppression affects distribution severity which may accelerate progression towards atrophic gastritis. chapter will discuss issue, conclude pylori-positive GORD require maintenance acid-suppressing drug eradication.