Affinity medicant conjugate
作者： Michael Kelner
DOI:
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摘要: In an embodiment of the invention, a composition for treating cell population comprises Affinity Medicant Conjugate (AMC). The medicant moiety can be toxin including acylfulvene or drug moiety. affinity antibody, binding protein, steroid, lipid, growth factor, peptide non peptidic. covalently bound to via linker. Novel linkers that directed cysteine, arginine lysine residues based on solution pH allow greater flexibility in preserving and/or generating specific epitopes AMC.
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