Apparatus for treating biological samples comprises substrate forming complex with structure in sample, system liberating biological molecules, substrate which forms complexes with them and system producing magnetic field to move substrates
作者： Thomas Ehben , Christian Dr. Zilch
DOI:
关键词:
摘要: Apparatus for treating samples analysis comprises: (A) a first substrate which forms complex with structure in the sample; (B) system liberating biological molecule structure; (C) second molecule; and (D) producing magnetic field moves two substrates. Independent claims are included for: (1) method using apparatus comprises binding to substrate, moving product field, molecules forming from it substrate; (2) analyzing comprising them identifying molecules.
lens.org参考文章(8)
Amar Rida, Martin Gijs, Victor Fernandez, Magnetic bead manipulation and transport device ,(2003)
Martin A. M. Gijs, Magnetic bead handling on-chip: new opportunities for analytical applications Microfluidics and Nanofluidics. ,vol. 1, pp. 22- 40 ,(2004) , 10.1007/S10404-004-0010-Y
Jin-Woo Choi, Kwang W. Oh, Jennifer H. Thomas, William R. Heineman, H. Brian Halsall, Joseph H. Nevin, Arthur J. Helmicki, H. Thurman Henderson, Chong H. Ahn, An integrated microfluidic biochemical detection system for protein analysis with magnetic bead-based sampling capabilities Lab on a Chip. ,vol. 2, pp. 27- 30 ,(2002) , 10.1039/B107540N
H. Lee, A. M. Purdon, R. M. Westervelt, Manipulation of biological cells using a microelectromagnet matrix Applied Physics Letters. ,vol. 85, pp. 1063- 1065 ,(2004) , 10.1063/1.1776339
Robin Hui Liu, Jianing Yang, Ralf Lenigk, Justin Bonanno, Piotr Grodzinski, Self-contained, fully integrated biochip for sample preparation, polymerase chain reaction amplification, and DNA microarray detection. Analytical Chemistry. ,vol. 76, pp. 1824- 1831 ,(2004) , 10.1021/AC0353029
Thomas Smekal, Piotr Grodzinski, Jeremy Burdon, Vijay Nair, Sean Gallagher, Robert Marrero, Yuk-Tong Chan, Xunhu Dai, Barbara Foley Barenburg, David Rhine, Microfluidic devices with monolithic microwave integrated circuits ,(2001)
Piotr Grodzinski, Jeremy W. Burdon, Rong-Fong Huang, Robert Marrero, Cynthia G. Briscoe, Barbara Foley, George Hawkins, Todd Tuggle, Peter Kahn, Huinan Yu, Mark W. Mcgarry, Tony Chan, Multilayered microfluidic devices for analyte reactions ,(2000)
Kristian Smistrup, Ole Hansen, Henrik Bruus, Mikkel F. Hansen, Magnetic separation in microfluidic systems using microfabricated electromagnets—experiments and simulations Journal of Magnetism and Magnetic Materials. ,vol. 293, pp. 597- 604 ,(2005) , 10.1016/J.JMMM.2005.01.079