Site of action of a ribosomal RNA methylase responsible for resistance to erythromycin and other antibiotics.
作者： R Skinner , E Cundliffe , F J Schmidt
DOI: 10.1016/S0021-9258(17)44232-3
关键词:
摘要: The enzyme which confers resistance to erythromycin in the producing organism Streptomyces erythraeus dimethylates a single adenine residue Bacillus stearothermophilus 23 S rRNA. This corresponds Ade 2058 Escherichia coli RNA. methylase responsible for macrolides, lincomycin, and streptogramin B-related antibiotics Staphylococcus aureus also acts at this site.
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