Antibodies to LRP6
作者： Minke Binnerts , Arie Abo
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摘要: Anti-LRP6 antibodies and antigen-binding fragments thereof, as well pharmaceutical compositions comprising such are described. These anti-LRP6 can be used to enhance Wnt activity and/or antagonize Dkk1 activity. Also described methods of therapy using regions bind modulate Wnt/LRP6 signaling promote tissue homeostasis, regeneration repair in diseases as, but not limited to, bone disorders, osteoporosis, rheumatoid arthritis, osteolytic lesions caused by osteoarthritis multiple myeloma, gastrointestinal disease wound healing.
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