Simulated biological dissolution and absorption system

摘要: The invention relates to a system and method for assessing simulated biological dissolution of pharmaceutical formulation absorption pharmaceutically active compound therefrom. comprises chamber cell culture chamber. Within the chamber, profile (or drug) is determined. may be absorbed transported by monolayer. includes tubular filter which permeable medium capable supporting monolayer on its interior surface. Insertion into housing forms an apical filter, basal between wall housing. rotates about axis within substantially parallel direction media flow through flowing from contains provided rate appearance in outflowing analysed determine compound.