A common pathophysiology for full thickness rectal prolapse, anterior mucosal prolapse and solitary rectal ulcer.

摘要: Anorectal pressures at rest, during conscious contraction of the external sphincter, serial distension rectum and straining to inflate a balloon were measured in 56 patients (21 with full thickness rectal prolapse, 24 anterior mucosal 11 solitary ulcer) 30 normal subjects. Both basal squeeze significantly lower three groups compared matched controls (P less than 0.05). During increases intra-abdominal pressure, anal pressure remained above maximum 0.05) controls, highest being recorded most caudal channels. In contrast, tended be this manoeuvre prolapse ulcer, channels nearest rectum. rectum, 64 per cent 75 76 but only 10 showed repetitive contractions. The always higher subjects not patients. threshold volume required cause desire defaecate tolerable each patient groups, similarity results from ulcer support hypothesis that they share common pathophysiology. is hypersensitive hyper-reactive, weakness sphincter creates conditions for occur into or through canal.