Effect of lack of vision and of occipital lobectomy upon recovery from unilateral labyrinthectomy in rhesus monkey

摘要: 1. We investigated the influence of visual experience upon vestibular compensation in monkeys. Two paradigms were used to elicit adaptation: artificially imposed motion images retina during head rotation and unilateral labyrinthectomy. groups animals investigated: monkeys that underwent a bilateral occipital lobectomy intact without cortical lesion. Occipital alone caused only minor change vestibuloocular reflex (VOR); gain (eye vel/head vel) decreased slightly (10-15%) for high speeds (180-300 degrees/s). 2. In response 4-h period continuous oscillation (0.25 Hz, 30 degrees/s) with scene made move phase (X0 viewing) or out (X2 viewing), showed an average 40% decrease increase, respectively, VOR measured darkness. After this adaptive capability was diminished, primarily increasing after X2 viewing (42% preop 13% postop). 3. Unilateral labyrinthectomy either occipital-lobectomized otherwise led static imbalance initial (18- 20-h postlesion) values spontaneous nystagmus 22-62 degrees/s darkness dynamic disturbance approximately 50% gain. Compensation both abnormalities studied three animals: previously kept light labyrinthectomy, dark 4 days then exposed light. Spontaneous disappeared at same rate each group animals. increased but not until they The some recovery (approximately 25-40%), low (30-60 performed had already compensated drop 0.5 any recurrence nystagmus. 4. Our results indicate is essential resolution Furthermore, geniculostriate pathways play major role providing information about velocities retinal image necessary acquisition adaptation.(ABSTRACT TRUNCATED AT 400 WORDS)