Overweight treated with energy restriction and a dietary fibre supplement: a 6-month randomized, double-blind, placebo-controlled trial.

摘要: Fifty-two (41 females, 11 males) overweight patients, mean body mass index (BMI) = 29.3, were treated for 6 months in a randomized, double-blind, placebo-controlled, parallel group design. The treatment consisted of an energy restricted diet and dietary fibre supplement amounting to 7 g/day. After the weight reduction fibre-treated group, 5.5 +/- 0.7 kg, was significantly higher than that placebo 3.0 0.5 kg (P 0.005). Both groups normotensive comparable commencing treatment, 126.5/75.6 2.0/1.3 mm Hg versus 126.7/78.7 2.5/1.6 Hg. changed blood pressure non-significantly. Hunger feelings using visual analogue scales (VAS) reduced from 139.8 8.2 cm 118.3 7.0 whereas significant increase 129.5 6.9 146.9 8.8 less 0.02) seen group. Side-effects predominantly gastrointestinal equally distributed two groups. It is concluded value management overweight, enhancing loss decreasing hunger feelings.