Cytogenetic Aberrations in the Cells of Liver and Spermatogenic Epithelium in Senescence Accelerated SAMP1 and SAMR1 Mice

作者: S. T. Zakhidov , T. L. Marshak , I. V. Uryvaeva , A. V. Gopko , M. L. Semenova

DOI: 10.1023/A:1021158727040

关键词:

摘要: It was shown that during ontogenesis, the mice prone to (SAMP1) and resistant (SAMR1) against accelerates senescence did not differ substantially in frequency of cytogenetic aberrations hepatocytes spermatogenic cells (spermatogonia round spermatids). These data suggest both lines, processes appearance, development, functioning complex biological systems, such as liver spermatogonic epithelium take place background high genetic instability. The role instability is discussed.

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