Bidirectional Introgressive Hybridization between a Cattle and Human Schistosome Species

摘要: Schistosomiasis is a disease of great medical and veterinary importance in tropical subtropical regions, caused by parasitic flatworms the genus Schistosoma (subclass Digenea). Following major water development schemes 1980s, schistosomiasis has become an important children living Senegal River Basin (SRB). During molecular parasitological surveys, nuclear mitochondrial markers revealed unexpected natural interactions between bovine human species: S. bovis haematobium, respectively. Hybrid schistosomes recovered from urine faeces intermediate snail hosts both parental species, Bulinus truncatus B. globosus, presented ITS rRNA sequence identical to while partial cox1 was identified as bovis. Molecular data suggest that hybrids are not 1st generation result and/or hybrid backcrosses, indicating stable zone. Larval stages with reverse genetic profile were also found suggested be F1 progeny. The provide indisputable evidence for occurrence bidirectional introgressive hybridization species. species have been infecting truncatus, now very abundant throughout SRB. recent increase urinary villages along SRB could therefore direct effect increased transmission through truncatus. Hybridization under laboratory conditions shown heterosis (higher fecundity, faster maturation time, wider host spectrum), having implications on prevalence, pathology treatment. If this new exhibits same vigour, it develop into emerging pathogen, necessitating further control strategies zones where overlap.