Cellular retinol-binding protein. Quantitation and distribution.
作者： U Eriksson , K Das , C Busch , H Nordlinder , L Rask
DOI: 10.1016/S0021-9258(18)90717-9
关键词:
摘要: The distribution of cellular retinol-binding protein was localized in three tissues involved the transport vitamin A using peroxidase-antiperoxidase technique. In addition, a sensitive radioimmunoassay developed to quantitate various tissues. liver, found hepatocytes and perisinusoidal fat-storing cells. columnar epithelial cells jejunum proximal tubuli also exhibit high concentrations protein. Estimations content from normal retinol-deficient rats showed that retinol status did not affect tissue levels or subcellular distribution. appearance amounts this dietary uptake, storage, mobilization, resorption suggest one function is act as vehicle intracellular through these organs.
sci-hub.st 参考文章(37)
N. Adachi, J.E. Smith, D. Sklan, D.S. Goodman, Radioimmunoassay studies of the tissue distribution and subcellular localization of cellular retinol-binding protein in rats. Journal of Biological Chemistry. ,vol. 256, pp. 9471- 9476 ,(1981) , 10.1016/S0021-9258(19)68786-7
L Rask, P A Peterson, In vitro uptake of vitamin A from the retinol-binding plasma protein to mucosal epithelial cells from the monkey's small intestine. Journal of Biological Chemistry. ,vol. 251, pp. 6360- 6366 ,(1976) , 10.1016/S0021-9258(20)81869-9
Pedro Cuatrecasas, Protein Purification by Affinity Chromatography Journal of Biological Chemistry. ,vol. 245, pp. 3059- 3065 ,(1970) , 10.1016/S0021-9258(18)63022-4
Kuni Takahashi, Shoji Odani, Teruo Ono, Primary structure of rat liver Z-protein. A low-Mr cytosol protein that binds sterols, fatty acids and other small molecules. FEBS Letters. ,vol. 140, pp. 63- 66 ,(1982) , 10.1016/0014-5793(82)80521-8
D E Ong, F Chytil, Retinoic acid-binding protein in rat tissue. Partial purification and comparison to rat tissue retinol-binding protein. Journal of Biological Chemistry. ,vol. 250, pp. 6113- 6117 ,(1975) , 10.1016/S0021-9258(19)41166-6
Helen S. Huang, DeWitt S. Goodman, VITAMIN A AND CAROTENOIDS. I. INTESTINAL ABSORPTION AND METABOLISM OF 14C-LABELLED VITAMIN A ALCOHOL AND BETA-CAROTENE IN THE RAT. Journal of Biological Chemistry. ,vol. 240, pp. 2839- 2844 ,(1965) , 10.1016/S0021-9258(18)97256-X
D E Ong, J A Crow, F Chytil, Radioimmunochemical determination of cellular retinol- and cellular retinoic acid-binding proteins in cytosols of rat tissues. Journal of Biological Chemistry. ,vol. 257, pp. 13385- 13389 ,(1982) , 10.1016/S0021-9258(18)33460-4
R K Ockner, J A Manning, J P Kane, Fatty acid binding protein. Isolation from rat liver, characterization, and immunochemical quantification. Journal of Biological Chemistry. ,vol. 257, pp. 7872- 7878 ,(1982) , 10.1016/S0021-9258(18)34463-6
D.E. Ong, F. Chytil, Cellular retinol-binding protein from rat liver. Purification and characterization. Journal of Biological Chemistry. ,vol. 253, pp. 828- 832 ,(1978) , 10.1016/S0021-9258(17)38178-4
Adrian J. Lamb, Piyaratana Apiwatanaporn, James A. Olson, Induction of Rapid, Synchronous Vitamin A Deficiency in the Rat Journal of Nutrition. ,vol. 104, pp. 1140- 1148 ,(1974) , 10.1093/JN/104.9.1140