The effect of tryptophan on postoperative endodontic pain

作者: Stephen E. Shpeen , Donald R. Morse , M. Lawrence Furst

DOI: 10.1016/0030-4220(84)90342-6

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摘要: Abstract Fifty consecutive patients requiring nonsurgical endodontic therapy were the subjects of this pain-control study. Twenty-five received 3 gm tryptophan in divided 0.5-gm doses over a 24-hour period, beginning before start treatment. The other twenty-five an identically appearing placebo on same dosage schedule. Pain intensity was evaluated by scale 0 to 10 (0 = no pain, severe pain) (1) prior treatment, (2) after 24 hours, and (3) 1 week later. Results showed that most meaningful difference found at when group significantly better than (F 7.46, df 1.96, p

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