Vitamin D and the nervous system.

摘要: Objective: to summarise the activities that Vitamin D (VD) carries out in brain and clarify potential role of VD neurological diseases. Methods: a literature research has been performed Pubmed using following keywords: 'Vitamin D', 'nervous system', 'brain'. Results: studies reviewed show contributes cerebral activity both embryonic adult brain, helping connectivity neural circuits responsible for locomotor, emotional reward-dependent behavior. Low serum levels have found patients affected by Alzheimer Disease, Parkinson Multiple Sclerosis, Autism Spectrum Disorders, Sleep Disorders Schizophrenia. Discussion: findings are controversial should be interpreted with caution, since most observational study set few interventional available, producing conflicting results. Overall, it can stated diseases is mostly unclear further randomised controlled trials needed understand better whether supplementation treatment useful disorders.