The role of a prostaglandin E1 deficiency in schizophrenia: interactions with dopamine and opiates
作者： D. F. Horrobin , M. S. Manku , M. Oka , S. C. Cunnane
DOI: 10.1007/978-94-009-8706-7_1
关键词:
摘要: There is evidence for a prostaglandin (PG) E1 deficiency in schizophrenia. Dopamine able to antagonize some of the effects PGE1 on excitable tissues and fundamental problem may therefore be an elevated dopamine : ratio. Schizophrenia should made worse by factors which raise this ratio alleviated lower it. Opiates various dietary deficiencies formation whereas prolactin melatonin enhance Most existing antischizophrenic drugs function because they have three separate actions will tend effective dopamine/PGE1 They block receptors, secretion secretion. This concept leads new therapeutic strategies seem worthy trial.
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