A pilot randomized controlled trial of a tailored smoking cessation program for people living with HIV in the Washington, D.C. metropolitan area.

摘要: OBJECTIVE Morbidity and mortality from smoking-related diseases among people living with HIV (PLWH) in the U.S. surpasses that due to itself. Conventional smoking cessation treatments have not demonstrated strong efficacy PLWH. We conducted a pilot randomized controlled trial (RCT) evaluate tailored intervention based on minority stress model. compared standard of care counseling (SOC) (TI) including one face-to-face session incorporating cognitive behavioral therapy build resilience, 30 days 2-way text messaging. RESULTS The primary outcome was cessation. Secondary outcomes included cigarettes per day (CPD), exhaled carbon monoxide (CO), self-efficacy. A total 25 participants were enrolled (TI:11, SOC:14), 2 lost follow-up. There no significant differences quit rates between study groups. However, there significantly greater decrease CPD TI versus SOC (13.5 vs. 0.0, p-value:0.036). Additionally, self-efficacy increased both groups (TI p-value:0.012, p-value:0.049) CO decreased p-value: < 0.001, p-value:0.049). This shows promise support larger is needed fully this approach. CLINICAL TRIAL Trial Registration: Retrospectively registered (10/20/2020) NCT04594109.