Genome Analysis and Phylogenetic Relatedness of Gallibacterium anatis Strains from Poultry

摘要: Peritonitis is the major disease problem of laying hens in commercial table egg and parent stock operations. Despite its importance, etiology pathogenesis this have not been completely clarified. Although avian pathogenic Escherichia coli (APEC) isolates incriminated as causative agent hen peritonitis, Gallibacterium anatis are frequently isolated from peritonitis lesions. recent studies suggesting a role for G. little known about organism’s virulence mechanisms, genomic composition population dynamics. Here, we compared genome sequences three an effort to understand mechanisms identify novel antigenic traits. A multilocus sequence typing method was also established used characterize genotypic relatedness 71 Iowa 18 international reference isolates. Genomic comparisons suggest that highly diverse bacterial species, with some strains possessing previously described potential factors, but core containing several candidates. Multilocus effectively distinguished 82 types clonal complexes anatis, clones seemed predominate among populations layers Iowa. Biofilm formation resistance antimicrobial agents observed clades. Overall, diversity suggests multiple lineages exist differing towards birds.