摘要: A detailed knowledge of the incidence, distribution, and natural history neoplasia throughout animal kingdom is central importance in gaining an understanding cancer as a biological process. Examples abnormal growth have been encountered many taxonomic groups animals at every level complexity. However, except for mammals, study neoplasia, especially lower vertebrates, to large extent descriptive, haphazard, incomplete. In this chapter, we will deal with some aspects biology poikilotherms. As shall see, task becomes increasingly difficult approach more primitive vertebrates invertebrates because there are significant gaps our their patterns response injury. Further, forms life, precise classification disturbances tissue neoplastic vast structural functional differences that separate these organisms from familiar well-studied higher This state affairs has become particularly frustrating recent years view rapid advances cell which emphasize unity basic organization function systems striking similarities such. regard, it worth recalling inflammatory reaction observed water flea (Daphnia), well sequential reactions protein synthesis elucidated biochemical studies Escherichia coli, directly applicable phenomena animals, including since they appear copied great fidelity evolutionary development life.