Epidemiologic Pathology of Gastric Ulcer and Gastric Carcinoma Among Japanese in Hawaii2

摘要: This case-control study of Hawaiian Japanese indicated that gastric ulcer in the proximal portion pyloric antrum has features similar to those cancer. Such ulcers occurred at sites most frequently and severely affected by intestinal metaplasia, although metaplasia tended be more extensive with cancer than ulcer. Metaplastic mucosa was vulnerable action pepsin acid normal mucosa. The risk ulceration would rise when a sufficiently lagrge area intestinalized corpus continued produce significant quantities these substances. showed strong association between salt intake, ulcer, metaplasia. Significant but less dramatic associations were demonstrated use traditional foods smoking. question raised as whether promotes or it potentiates mutagen causes