Cancer dissemination during laparoscopic surgery: tubes, gas, and cells.

作者: Eduardo M Targarona , Joaquín Martínez , Alfons Nadal , Carmen Balagué , Antonio Cardesa

DOI: 10.1007/S002689900349

关键词:

摘要: n = 11) or laparotomy (group 2, 12). A Medline review of all experimental studies about the risk cancer dissemination during laparoscopic surgery was undertaken. Both models were associated with implants in parietal wounds [1/11 group 1 (9%) vs. 1/12 2 (8%), p NS]. Analysis current literature confirms that laparoscopy is abdominal cell mobilization, and cells can be recovered trocars, filtered exhaust gas, instruments. Postoperative immunosuppression, biologic aggressiveness tumor, gas used for also influence tumoral growth. Port-site metastases are secondary to multiple factors, including technical skill surgeon, properties tumors, local environmental aspects. Undoubtedly, help disseminate aggressive tumors should reserved diagnostic staging procedures treatment low-grade malignant tumors. Therapeutic resection, especially colon cancer, restricted prospective randomized trials until there enough hard data rule out clinical importance this potentially severe complication.

参考文章(35)
A. Cuschieri, Diagnosis and Staging of Tumors by Laparoscopy Surgical Innovation. ,vol. 1, pp. 3- 12 ,(1994) , 10.1177/155335069400100103
John D. F. Allendorf, Marc Bessler, Richard L. Whelan, Matthew Trokel, Dennis A. Laird, Mary Beth Terry, Michael R. Treat, Better preservation of immune function after laparoscopic-assisted vs. open bowel resection in a murine model Diseases of the Colon & Rectum. ,vol. 39, pp. S67- S72 ,(1996) , 10.1007/BF02053809
Irwin R. Berman, Cancer recurrence after laparoscopic colectomy—A missing link? Diseases of The Colon & Rectum. ,vol. 38, pp. 330- 331 ,(1995) , 10.1007/BF02055616
H. C. Umpleby, B. Fermor, M. O. Symes, R. C. N. Williamson, Viability of exfoliated colorectal carcinoma cells British Journal of Surgery. ,vol. 71, pp. 659- 663 ,(2005) , 10.1002/BJS.1800710902
M. Doudle, G. King, W. M. Thomas, P. Hewett, The movement of mucosal cells of the gallbladder within the peritoneal cavity during laparoscopic cholecystectomy Surgical Endoscopy and Other Interventional Techniques. ,vol. 10, pp. 1092- 1094 ,(1996) , 10.1007/S004649900247
E. J. M. Nieveen Van Dijkum, L. Th. De Wit, H. Obertop, D. J. Gouma, Port‐site metastases following diagnostic laparoscopy British Journal of Surgery. ,vol. 83, pp. 1793- 1794 ,(2005) , 10.1002/BJS.1800831242
R. S. Savalgi, Mechanism of Abdominal Wall Recurrence After Laparoscopic Resection of Colonic Cancers. Seminars in Laparoscopic Surgery. ,vol. 2, pp. 158- 162 ,(1995) , 10.1177/155335069500200303
A.J. Walt, The Gerald Marks Lecture. New technology. Temptations, challenges, and educational implications. Surgical Endoscopy and Other Interventional Techniques. ,vol. 8, pp. 1375- ,(1994) , 10.1007/BF00187339
Asbun Hj, Bowyer Mw, Shibata G, Knolmayer Tj, An experimental model of cellular aerosolization during laparoscopic surgery. Surgical laparoscopy & endoscopy. ,vol. 7, pp. 399- 402 ,(1997)
Balagué C, Targarona Em, Martinez J, Pera M, Trias M, Port site metastasis. An unresolved problem in laparoscopic surgery : A review International Surgery. ,vol. 80, pp. 315- 321 ,(1995)