Synthesis of 3‐(Tosylalkyl)indazoles and their Desulfonylation Reactions – A New Entry to 3‐Substituted Indazoles by an Unprecedented Friedel–Crafts Process
作者： Silvia Campetella , Alessandro Palmieri , Marino Petrini
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摘要: Reaction of indazoles with aldehydes in the presence p-toluenesulfinic acid affords corresponding sulfonyl satisfactory yields. The reported Friedel–Crafts process is rather unusual on because reduced electronic density heterocycle. obtained can be desulfonylated under reductive conditions, finally leading to 3-alkylated indazoles.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
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