Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration
作者： Amy M. Spinelli , José C. González-Cobos , Xuexin Zhang , Rajender K. Motiani , Sarah Rowan
DOI: 10.1007/S00424-012-1160-5
关键词:
摘要: … PDGF activated inwardly rectifying highly Ca 2+ -selective CRAC currents in ASMC. Furthermore, we show that PDGF-activated Ca 2+ entry and CRAC currents were significantly …
elsevier.com
springer.com
sci-hub.se 参考文章(75)
Michael J. Holtzman, Derek E. Byers, Loralyn A. Benoit, John T. Battaile, Yingjian You, Eugene Agapov, Chaeho Park, Mitchell H. Grayson, Edy Y. Kim, Anand C. Patel, Chapter 5 Immune Pathways for Translating Viral Infection into Chronic Airway Disease Advances in Immunology. ,vol. 102, pp. 245- 276 ,(2009) , 10.1016/S0065-2776(09)01205-X
J. K. Bentley, M. B. Hershenson, Airway smooth muscle growth in asthma: proliferation, hypertrophy, and migration. Proceedings of the American Thoracic Society. ,vol. 5, pp. 89- 96 ,(2008) , 10.1513/PATS.200705-063VS
Qinghua Hu, Gemin Zheng, Jay L. Zweier, Shailesh Deshpande, Kaikobad Irani, Roy C. Ziegelstein, NADPH Oxidase Activation Increases the Sensitivity of Intracellular Ca2+Stores to Inositol 1,4,5-Trisphosphate in Human Endothelial Cells Journal of Biological Chemistry. ,vol. 275, pp. 15749- 15757 ,(2000) , 10.1074/JBC.M000381200
K. Mahn, S. J. Hirst, S. Ying, M. R. Holt, P. Lavender, O. O. Ojo, L. Siew, D. E. Simcock, C. G. McVicker, V. Kanabar, V. A. Snetkov, B. J. O'Connor, C. Karner, D. J. Cousins, P. Macedo, K. F. Chung, C. J. Corrigan, J. P. T. Ward, T. H. Lee, Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma Proceedings of the National Academy of Sciences of the United States of America. ,vol. 106, pp. 10775- 10780 ,(2009) , 10.1073/PNAS.0902295106
Suzanne J. House, Marie Potier, Jonathan Bisaillon, Harold A. Singer, Mohamed Trebak, The non-excitable smooth muscle: Calcium signaling and phenotypic switching during vascular disease Pflügers Archiv: European Journal of Physiology. ,vol. 456, pp. 769- 785 ,(2008) , 10.1007/S00424-008-0491-8
Christer Betsholtz, Insight into the physiological functions of PDGF through genetic studies in mice Cytokine & Growth Factor Reviews. ,vol. 15, pp. 215- 228 ,(2004) , 10.1016/J.CYTOGFR.2004.03.005
Jen Liou, Man Lyang Kim, Won Do Heo, Joshua T. Jones, Jason W. Myers, James E. Ferrell, Tobias Meyer, STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx Current Biology. ,vol. 15, pp. 1235- 1241 ,(2005) , 10.1016/J.CUB.2005.05.055
Martin Muik, Marc Fahrner, Isabella Derler, Rainer Schindl, Judith Bergsmann, Irene Frischauf, Klaus Groschner, Christoph Romanin, A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels Journal of Biological Chemistry. ,vol. 284, pp. 8421- 8426 ,(2009) , 10.1074/JBC.C800229200
I Ohno, Y Nitta, K Yamauchi, H Hoshi, M Honma, K Woolley, P O'Byrne, J Dolovich, M Jordana, G Tamura, Eosinophils as a potential source of platelet-derived growth factor B-chain (PDGF-B) in nasal polyposis and bronchial asthma. American Journal of Respiratory Cell and Molecular Biology. ,vol. 13, pp. 639- 647 ,(1995) , 10.1165/AJRCMB.13.6.7576701
X. Wu, P. Eder, B. Chang, J. D. Molkentin, TRPC channels are necessary mediators of pathologic cardiac hypertrophy Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 7000- 7005 ,(2010) , 10.1073/PNAS.1001825107