Effects of posttraining epinephrine injections on retention of avoidance training in mice

摘要: These experiments examined the effects, on retention, of posttraining epinephrine injections in mice. Mice were trained a one-trial inhibitory (passive) avoidance task and retention performance was measured 24 hr after training. In first experiment, animals received an immediate injection saline or (3–1000 μ g/kg). An intermediate dose (30 g/kg) enhanced later high (1000 impaired performance. second (50 again if treatment administered immediately training but not delayed by 10 30 min A higher (500 had no effect drug However, this did enhance Thus, dose—response characteristics enhancement vary with time findings are consistent general view that hormonal consequences may modulate storage recent information and, furthermore, treatments affect memory through mechanisms which interact responses to