Pilot study of a new acrylic cage in a dog cervical spine fusion model.

摘要: STUDY DESIGN: An experimental pilot study using an acrylic interbody cage in a dog cervical spine fusion model. OBJECTIVE: To compare bony autologous bone grafting with novel terms of preservation disc height, biomechanical properties, and histologic characteristics. SUMMARY OF BACKGROUND DATA: Degenerative diseases intervertebral discs are commonly treated by anterior decompression fusion. restore physiologic height achieve fusion, the is replaced graft, cement, cages, or other materials. The advantages cement contrast to graft cages immediate stability less subsidence, although real cannot be achieved. overcome this problem, we designed new, inexpensive cage. METHODS: Ten adult hybrid dogs underwent C3/C4 (5 dogs) C4/C5 discectomy made polymethylmethacrylate filled (n=5, group1) iliac group 2). Dynamic functional x-ray was obtained 1 12 weeks after operation. After weeks, animals were killed sites evaluated quantitative computed tomographic scanning evaluate mineral density. Subsistence quantified testing. Histopathologic analysis used possible foreign body reactions associated RESULTS: led significantly higher space subsidence than (P<0.021). Bone density greater cage, but difference not statistically significant. Histologically, new tissue hyaline cartilage seen inside accompanied mild chronic inflammation. CONCLUSIONS: showed mechanical stiffness grafting. Additional studies more subjects longer follow-up periods needed cost effectiveness polyetheretherketone devices.