Protein adsorption on electrospun zinc doped hydroxyapatite containing nylon 6 membrane: kinetics and isotherm.

作者: Hamid Esfahani , Molamma P. Prabhakaran , Esmaeil Salahi , Ali Tayebifard , Mansour Keyanpour-Rad

DOI: 10.1016/J.JCIS.2014.12.014

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摘要: Abstract Surface modification of electrospun polymeric membrane surfaces is a critical step towards the separation process including protein adsorption. In this study, Nylon fibers was incorporated with positively charged zinc doped hydroxyapatite (HAp) nanoparticles to study adsorption negatively proteins, namely bovine serum albumin (BSA). Effects amount within atomic structure HAp ( n ZH;  = 0, 4, 8 At.%) evaluated on produced scaffolds and consequently The results showed that ability adsorb BSA increased incorporation ZH nylon structure. This phenomenon appeared be relate different electrostatic charge not physical characteristic scaffolds. (N-4ZH) by highest zeta (ξ) potential adsorbed maximum protein. best fitted pseudo-second order kinetic model. experimental isotherm data were further analyzed using Langmuir Freundlich equations. By comparing correlation coefficients obtained for each linear transformation analysis, it found equation fit equilibrium model described these membranes.

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