Lipoprotein(a) is an independent risk factor for myocardial infarction at a young age.

摘要: We quantified lipoprotein(a) [Lp(a)] immunochemically in young (less than 46 y) male survivors of myocardial infarction and age-matched controls recruited from participants the Prospective Cardiovascular Munster (PROCAM) study. further determined apolipoprotein E polymorphism measured triglycerides, total cholesterol, high- low-density lipoprotein cholesterol (HDL LDL), apolipoproteins AI, AII, B serum these subjects. Lp(a) concentrations were not correlated with other well-recognized risk factors for early such as AI B, LDL HDL cholesterol. Apolipoprotein did affect concentrations, but had a major influence on concentration. influenced by age. Our data suggest that (a) an increased concentration constitutes independent factor (b) (apolipoprotein B) are under separate metabolic control.