Combine and Free-Wilson QSAR Analysis of Nuclear Receptor-DNA Binding
作者： Sanja Tomić , Lennart Nilsson , Rebecca C. Wade
DOI: 10.1007/978-1-4615-4141-7_35
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摘要: Specific binding of transcription factors to DNA is crucial for gene regulation. We have studied the specificity from nuclear receptor family using two QSAR methods: a) a Free-Wilson like method and b) Comparative Binding Energy (COMBINE)1 analysis.
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sci-hub.st 参考文章(3)
J Zilliacus, A.P. Wright, U Norinder, J.A. Gustafsson, J Carlstedt-Duke, Determinants for DNA-binding site recognition by the glucocorticoid receptor. Journal of Biological Chemistry. ,vol. 267, pp. 24941- 24947 ,(1992) , 10.1016/S0021-9258(19)73988-X
Angel R. Ortiz, M. Teresa Pisabarro, Federico Gago, Rebecca C. Wade, Prediction of drug binding affinities by comparative binding energy analysis Journal of Medicinal Chemistry. ,vol. 38, pp. 2681- 2691 ,(1995) , 10.1021/JM00014A020
Johanna Zilliacus, Anthony P. H. Wright, Jan Carlstedt-Duke, Lennart Nilsson, Jan-Åke Gustafsson, Modulation of DNA‐binding specificity within the nuclear receptor family by substitutions at a single amino acid position Proteins. ,vol. 21, pp. 57- 67 ,(1995) , 10.1002/PROT.340210107