Decreased Nucleotide and Expression Diversity and Modified Coexpression Patterns Characterize Domestication in the Common Bean

摘要: Using RNA sequencing technology and de novo transcriptome assembly, we compared representative sets of wild domesticated accessions common bean (Phaseolus vulgaris) from Mesoamerica. was extracted at the first true-leaf stage, assembly used to develop a reference transcriptome; final data set consists ∼190,000 single nucleotide polymorphisms 27,243 contigs in expressed genomic regions. A drastic reduction diversity (∼60%) is evident for form, with almost 50% that are polymorphic were brought fixation by domestication. In parallel, effects domestication decreased gene expression (18%). While coexpression networks demonstrate similar seminal network properties, they show distinct community structures enriched different molecular functions. After simulating demographic dynamics during domestication, found 9% genes actively selected We also selection induced further (26%) associated 5-fold enrichment differentially genes. there substantial evidence positive few cases, this has increased pool target loci abiotic stress responses, flowering time, morphology.