Hydrogel encapsulated cells and anti-inflammatory drugs

作者: Robert S. Langer , Tram T. Dang , Daniel G. Anderson

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摘要: A composition containing biocompatible hydrogel encapsulating mammalian cells and anti-inflammatory drugs is disclosed. The encapsulated have reduced fibrotic overgrowth after implantation in a subject. compositions contain having therein or polymeric particles loaded with drugs. are released from the transplantation an amount effective to inhibit fibrosis of for at least ten days. Methods identifying selecting suitable drug-loaded prevent also described. treating disease subject disclosed that involve administering therapeutically

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