Effect of treatment willingness on specialist assessment and treatment uptake for hepatitis C virus infection among people who use drugs: the ETHOS study

摘要: SUMMARY. Among people who inject drugs (PWID) with chronic HCV, the association between HCV treatment willingness and intent, specialist assessment were evaluated. The Enhancing Treatment for Hepatitis C in Opioid Substitution Settings (ETHOS) is a prospective observational cohort. Recruitment was through six opioid substitution clinics, two community health centres one Aboriginal controlled organisation Australia. Analyses performed using logistic regression. 415 participants (mean age 41 years, 71% male), 67% ‘definitely willing’ to receive 70% reported plans initiate therapy 12 months postenrolment. Those definitely willing more likely undergo (64% vs 32%, P < 0.001) (36% 9%, 0.001), compared those lower willingness. early (65% 27%, 5%, without plans. In adjusted analyses, independently predicted (aOR 3.06, 95% CI 1.90, 4.94) uptake 4.33, 2.14, 8.76). analysis, having 4.38, 2.63, 7.29) 9.79, 3.70, 25.93). high treatment. Strategies enhanced care should be developed an initial focus on increase among less willing.