Antimicrobial impregnated catheters and other medical implants

作者: Issam Raad , Rabih O. Darouiche

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摘要: A non-metallic antimicrobial impregnated medical implant, such as a catheter, and method for impregnating implant with an agent is provided. The making the comprises steps of forming composition effective concentration to inhibit growth organisms, staphylococci, other gram-positive bacteria, gram-negative bacilli Candida applying at least portion under conditions where permeates material implant. formed by dissolving in organic solvent, adding penetrating composition, alkalinizing composition. preferably heated temperature between about 30° C. 70° prior enhance adherence material. After removed from solution, allowed dry then rinsed liquid milked remove excess granular deposits ensure uniform color

参考文章(11)
Richard J. Whitbourne, Margaret A. Mangan, Anti-thrombogenic, anti-microbial compositions containing heparin ,(1989)
Alan D. Olstein, Polymeric biocidal agents ,(1991)
Christopher M. Hobot, Allan H. Jevne, Matthew A. Bergan, James R. Keogh, John W. Eaton, Method for administering a bioactive agent ,(1995)
Issam I. Raad, Rabih O. Darouiche, Antibacterial coated medical implants ,(1993)
Michael N. Helmus, Carol L. Raleigh, M. Joshua Tolkoff, Medical device polymer ,(1991)
Roger Bayston, Nancy Jane Grove, Antimicrobial device and method ,(1988)