Multimodal Volume-Aware Detection and Segmentation for Brain Metastases Radiosurgery

作者: Furen Xiao , Jen-Tang Lu , Feng-Ming Hsu , Shao-Lun Lu , Wei-Hung Weng

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摘要: Stereotactic radiosurgery (SRS), which delivers high doses of irradiation in a single or few shots to small targets, has been standard care for brain metastases. While very effective, SRS currently requires manually intensive delineation tumors. In this work, we present deep learning approach automated detection and segmentation metastases using multimodal imaging ensemble neural networks. order address multiple metastases, further propose volume-aware Dice loss optimizes model performance the information lesion size. This work surpasses current benchmark levels demonstrates reliable AI-assisted system treatment planning

参考文章(11)
Khan M. Iftekharuddin, Brian B. Avants, Max Wintermark, Doina Precup, Jayashree Kalpathy-Cramer, Antonio Criminisi, Michel Dojat, Ender Konukoglu, Polina Golland, Herve Delingette, Andac Hamamci, Nagesh K. Subbanna, Nicholas J. Tustison, Tal Arbel, Yuliya Burren, Darko Zikic, Duygu Sarikaya, Ben Glocker, Gabor Szekely, Joana Festa, Gozde Unal, Stefan Bauer, Cagatay Demiralp, Ezequiel Geremia, Bjoern H. Menze, Andras Jakab, Jamie Shotton, Marcel Prastawa, Jason J. Corso, Nicolas Cordier, Syed M. S. Reza, Michael Ryan, Stephen J. Price, Danial Lashkari, Senan Doyle, Lawrence Schwartz, D. Louis Collins, Hoo-Chang Shin, Keyvan Farahani, Xiaotao Guo, Marc-Andre Weber, Nicholas Ayache, Florence Forbes, Sergio Pereira, Owen M. Thomas, Roland Wiest, Johannes Slotboom, Christopher R. Durst, Nuno Sousa, Raphael Meier, Levente Lanczi, Elizabeth Gerstner, Tilak Das, Mauricio Reyes, Koen Van Leemput, Liang Zhao, Raj Jena, Jose Antonio Mariz, Flor Vasseur, Binsheng Zhao, Thomas J. Taylor, Nigel M. John, Nicole Porz, Dong Hye Ye, Tammy Riklin Raviv, Patricia Buendia, Justin Kirby, Carlos A. Silva, The Multimodal Brain Tumor Image Segmentation Benchmark (BRATS) IEEE Transactions on Medical Imaging. ,vol. 34, pp. 1993- 2024 ,(2015) , 10.1109/TMI.2014.2377694
Gisele C. Pereira, Melanie Traughber, Raymond F. Muzic, The role of imaging in radiation therapy planning: Past, present, and future BioMed Research International. ,vol. 2014, pp. 231090- 231090 ,(2014) , 10.1155/2014/231090
Xuling Lin, Lisa M. DeAngelis, Treatment of Brain Metastases Journal of Clinical Oncology. ,vol. 33, pp. 3475- 3484 ,(2015) , 10.1200/JCO.2015.60.9503
May N. Tsao, Dirk Rades, Andrew Wirth, Simon S. Lo, Brita L. Danielson, Laurie E. Gaspar, Paul W. Sperduto, Michael A. Vogelbaum, Jeffrey D. Radawski, Jian Z. Wang, Michael T. Gillin, Najeeb Mohideen, Carol A. Hahn, Eric L. Chang, Radiotherapeutic and surgical management for newly diagnosed brain metastasis(es): An American Society for Radiation Oncology evidence-based guideline Practical radiation oncology. ,vol. 2, pp. 210- 225 ,(2012) , 10.1016/J.PRRO.2011.12.004
Konstantinos Kamnitsas, Christian Ledig, Virginia FJ Newcombe, Joanna P Simpson, Andrew D Kane, David K Menon, Daniel Rueckert, Ben Glocker, None, Efficient Multi-Scale 3D CNN with Fully Connected CRF for Accurate Brain Lesion Segmentation Medical Image Analysis. ,vol. 36, pp. 61- 78 ,(2017) , 10.1016/J.MEDIA.2016.10.004
Özgün Çiçek, Ahmed Abdulkadir, Soeren S Lienkamp, Thomas Brox, Olaf Ronneberger, None, 3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation medical image computing and computer assisted intervention. pp. 424- 432 ,(2016) , 10.1007/978-3-319-46723-8_49
Shalini K. Vinod, Michael G. Jameson, Myo Min, Lois C. Holloway, Uncertainties in volume delineation in radiation oncology: A systematic review and recommendations for future studies Radiotherapy and Oncology. ,vol. 121, pp. 169- 179 ,(2016) , 10.1016/J.RADONC.2016.09.009
Yan Liu, Strahinja Stojadinovic, Brian Hrycushko, Zabi Wardak, Steven Lau, Weiguo Lu, Yulong Yan, Steve B. Jiang, Xin Zhen, Robert Timmerman, Lucien Nedzi, Xuejun Gu, A deep convolutional neural network-based automatic delineation strategy for multiple brain metastases stereotactic radiosurgery PLOS ONE. ,vol. 12, pp. e0185844- ,(2017) , 10.1371/JOURNAL.PONE.0185844
Odelin Charron, Alex Lallement, Delphine Jarnet, Vincent Noblet, Jean-Baptiste Clavier, Philippe Meyer, Automatic detection and segmentation of brain metastases on multimodal MR images with a deep convolutional neural network. Computers in Biology and Medicine. ,vol. 95, pp. 43- 54 ,(2018) , 10.1016/J.COMPBIOMED.2018.02.004
Dianne Hartgerink, Britt van der Heijden, Dirk De Ruysscher, Alida Postma, Linda Ackermans, Ann Hoeben, Monique Anten, Philippe Lambin, Karin Terhaag, Arthur Jochems, Andre Dekker, Janna Schoenmaekers, Lizza Hendriks, Jaap Zindler, Stereotactic Radiosurgery in the Management of Patients With Brain Metastases of Non-Small Cell Lung Cancer: Indications, Decision Tools and Future Directions. Frontiers in Oncology. ,vol. 8, pp. 154- 154 ,(2018) , 10.3389/FONC.2018.00154