Risk-based versus alternative algorithms for antibiotic prophylaxis among women seeking early suction abortion: a cost-effectiveness simulation.

作者: HEIDI B. FRIEDMAN , THOMAS L. GIFT , INNE SUSANTI , JUDITH N. WASSERHEIT

DOI: 10.1097/00007435-200112000-00009

关键词:

摘要: Background: Particularly in resource-poor settings, simple, inexpensive, and cost-effective algorithms are needed to direct antibiotic prophylaxis prevent sequelae of infections with Chlamydia trachomatis, Neisseria gonorrhoeae, bacterial vaginosis-associated organisms among women undergoing abortion. Goal: To assess the prevalence risk factors for seeking abortion Bali, Indonesia, use these data designing a risk-based algorithm. Study Design: A cross-sectional analysis data-based simulation alternative were performed. Results: The algorithm would have provided 70% (95% CI, 53-83%) cervical infection, 64% 54-74%) those vaginosis, 57% 42-72%) trichomoniasis. For was more cost effective than all others evaluated. cost-effectiveness acceptable vaginosis. Conclusions: Risk-based may be identifying likely benefit from preabortion prophylaxis. Prospective evaluation is validate findings.

参考文章(20)
K Petersen, L Heisterberg, Metronidazole prophylaxis in elective first trimester abortion. Obstetrics & Gynecology. ,vol. 65, pp. 371- 374 ,(1985)
George F. Sawaya, Karla Kerlikowske, Deborah Grady, David A. Grimes, Antibiotics at the time of induced abortion: the case for universal prophylaxis based on a meta-analysis. Obstetrics & Gynecology. ,vol. 87, pp. 884- 890 ,(1996)
Babill Stray-Pedersen, J. Biørnstad, Liv Kristiansen, Kirsti Hansen, T. Bergan, Marianne Dahl, G. Aanestad, Induced abortion: microbiological screening and medical complications. Infection. ,vol. 19, pp. 305- 308 ,(1991) , 10.1007/BF01645352
C A Spiegel, R Amsel, K K Holmes, Diagnosis of bacterial vaginosis by direct gram stain of vaginal fluid. Journal of Clinical Microbiology. ,vol. 18, pp. 170- 177 ,(1983) , 10.1128/JCM.18.1.170-177.1983
John Mullahy, The Negative Side of Cost-effectiveness Analysis JAMA: The Journal of the American Medical Association. ,vol. 277, pp. 1931- 1932 ,(1997) , 10.1001/JAMA.1997.03540480031025
Per-Göran Larsson, Jens-Jörgen Platz-Christensen, Henning Thejls, Urban Forsum, Carl Påhlson, Incidence of pelvic inflammatory disease after first-trimester legal abortion in women with bacterial vaginosis after treatment with metronidazole: a double-blind, randomized study. American Journal of Obstetrics and Gynecology. ,vol. 166, pp. 100- 103 ,(1992) , 10.1016/0002-9378(92)91838-2
K. A. Ryan, R. E. Roddy, L. Zekeng, S. S. Weir, U. Tamoufe, Characteristics associated with prevalent HIV infection among a cohort of sex workers in Cameroon. Sexually Transmitted Infections. ,vol. 74, pp. 131- 135 ,(1998) , 10.1136/STI.74.2.131
F. Lloyd, W. A. Liston, I. W. Smith, A. J. Macaulay, F. D. Johnstone, Screening for Chlamydia trachomatis in women referred for legal abortion Journal of Obstetrics and Gynaecology. ,vol. 11, pp. 224- 226 ,(1991) , 10.3109/01443619109013568
Suzanne M Garland, Sepehr Tabrizi, Julene Hallo, Shujun Chen, Assessment of Chlamydia trachomatis prevalence by PCR and LCR in women presenting for termination of pregnancy. Sexually Transmitted Infections. ,vol. 76, pp. 173- 176 ,(2000) , 10.1136/STI.76.3.173
P-G Larsson, B Bergman, U Forsum, J-J Platz-Christensen, C Påhlson, Mobiluncus and Cluecells as Predictors of PID After First‐Trimester Abortion Acta Obstetricia et Gynecologica Scandinavica. ,vol. 68, pp. 217- 220 ,(1989) , 10.3109/00016348909020992