PCR-Restriction Fragment Length Polymorphism Can Also Detect Point Mutation A2142C in the 23S rRNA Gene, Associated with Helicobacter pylori Resistance to Clarithromycin

作者: Armelle Ménard , Adriana Santos , Francis Mégraud , Mónica Oleastro

DOI: 10.1128/AAC.46.4.1156-1157.2002

关键词:

摘要: Clarithromycin resistance, the major cause of Helicobacter pylori treatment failure ([2][1], [7][2]), is attributed to point mutations within peptidyltransferase-encoding region in domain V 23S rRNA gene ([10][3], [15][4]). Three distinct have been found be associated

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