Host Control of the Replication of Group I RNA Phages

作者: Hanna Engelberg-Kulka , Rachel Schoulaker-Schwarz

DOI: 10.1007/978-1-4613-3888-8_14

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摘要: In this article we summarize our studies showing the involvement of Escherichia coli proteins in vivo replication group I RNA phages (MS2, f2 and R17). We used two methods investigation: first method, followed presence rifampin, a drug which completely inhibits host protein synthesis; second effect specific bacterial mutation (traD) on these phages. According to both methods, only was inhibited while that phage Qβ (group III) unaffected. This indicates use different for their replication. addition, showed traD also affects host’s membranes. discuss possibility membranes are involved

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