Defining radiographic incidence and progression of knee osteoarthritis: suggested modifications of the Kellgren and Lawrence scale

摘要: In the 1950s, Kellgren and Lawrence carried out first large-scale epidemiological studies of osteoarthritis. Obtaining x-rays on multiple subjects from populations various communities in England, they defined a grading scale for osteoarthritis that is still widely used called by their names, (K&L) scale.1 This osteophyte-based most large small-scale clinical to define whether present or absent radiograph. Unfortunately, neither nor subsequent users were consistent how described each grades. Importantly, grade 2, which usually defines present, it has been labelled as ‘definite osteophyte’ osteophyte with possible narrowing joint space’. As noted Schiphof colleagues,2 3 investigators have come up descriptions K&L these may identified somewhat different group persons radiographic knee osteoarthritis. With emergence longitudinal questions about new-onset disease progressive disease, was never designed address. Even so, many studies, especially investigations, identify knees disease. Framingham Rotterdam Studies,4 5 example, 2 had previously graded either grades 0 1. Study alternatively incidence new onset 1 0.5 Progression extant also characterised using progression one more often listed criterion …