Method of and apparatus for cell poration and cell fusion using radiofrequency electrical pulses

摘要: Disclosed are an apparatus and a method for the poration fusion of cells using radiofrequency electrical pulses. The electrodes can be hand held or part integrated equipment with special containers cells. electrodes, which positioned equal distance from each other, attached to power function generator. generator apply continuous AC field and/or pulsed across electrodes. alternating induces cell dielectrophoresis. porates fuses used fuse porate variety including erythrocyte ghosts, liposomes, vesicles, isolated cultured During fusions chemical agents antibodies, proteins, drugs, molecular probes, hormones, growth factors, DNA, RNA, enzymes, organic chemicals inorganic introduced into these also produce new species make hybridoma monoclonal antibodies.