摘要: Autoimmune hepatitis may have an aggressive course that can result in cirrhosis, liver failure, or requirement for transplantation. Prednisone alone a lower dose combination with azathioprine remains the preferred treatment of autoimmune hepatitis. Therapy to normalize biochemistry and histological findings reduces but does not eliminate occurrence relapse once off treatment. Treatment failure warrants re-assessment regarding accuracy original diagnosis exclusion variant forms other concurrent diseases. New immunosuppressive agents are being tested, site-specific molecular interventions will likely become feasible future.