Barotrauma, Volume Trauma and Their Relation to FRC

摘要: The term barotrauma (pressure induced injury) is often used in reference to complications of mechanical ventilation involving extravasation air from the lung (e.g., pulmonary interstitial emphysema, pneumomediastinum, subcutaneous pneumothorax). Macklin et al. proposed that high ventilatory pressures disrupt respiratory epithelium at interface between alveolar base and vascular sheath, thereby allowing track along bronchoalveolar sheaths dissect (or break free) into interstitial, vascular, mediastinal, peritoneal, retroperitoneal, pleural or spaces [1]. A number studies have supported an association peak airway pressures, PEEP, tidal volumes, minute [2, 3]. However, a recent prospective multivariate analysis patients receiving for greater than 24 hours found only presence ARDS correlate independently with risk developing pneumothorax [4]. Thus, it possible leaks noted prior was reflection severity underlying injury (necessitating use ventilation), rather effect causing barotrauma.