DOI: 10.1016/J.ACTATROPICA.2015.10.019
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摘要: Challenges of resistance to synthetic antimicrobials have opened new vistas in the search for natural products. This article rigorously reviews plants and other products used oral health: Punica granatum L. (pomegranate), Matricaria recutita (chamomile), Camellia sinensis (L.) Kuntze (green tea), chewing sticks made from Diospyros mespiliformis Hochst. ex A.D.C., lycioides Desf., Salvadora persica (miswak), honey propolis manuka tree (Leptospermum scoparium J.R. Forst. & G. Forst.), rhein Rheum rhabarbarum (rhubarb), dried fruits Vitis vinifera (raisins), essential oils, probiotics mushrooms. Further, review highlights Africa, Asia, Brazil, Mexico, Europe, Middle East. Some plants' antimicrobial properties chemical principles been elucidated. While use health is prominent resource-poor settings, testing mainly conducted following countries (in decreasing order magnitude): India, South Japan, France, Egypt, Iran, Kenya, Switzerland, Nigeria, Australia, Uganda, United Kingdom. exposes a dire gap more studies on clinical efficacy toxicity, emerging trend was noted: basic research done Europe Australia. China, India New Zealand generally conduct value addition fortification toothpastes. African focus bioprospecting primary production raw with efficacies. The East Egypt predominantly as sticks. More funding are needed field health, especially Africa where diseases fuelled by human immunodeficiency virus/acquired syndrome (HIV/AIDS).