Peripheral Biomarker Candidates of Posttraumatic Stress Disorder.

作者: Hee Jin Kang , Sujung Yoon , In Kyoon Lyoo

DOI: 10.5607/EN.2015.24.3.186

关键词:

摘要: There is high variability in the manifestation of physical and mental health problems following exposure to trauma disaster. Although most people may show a range acute symptoms aftermath traumatic events, chronic persistent disorders not be developed all individuals who were exposed events. The common long-term pathological consequence after posttraumatic stress disorder (PTSD). However, comorbid conditions including depression, anxiety disorder, substance use-related problems, variety other frequently observed with exposure. Post-traumatic syndrome (PTS) defined collectively as vast psychosocial that could experienced response It important predict will continue suffer from recover given heterogeneity symptom manifestations, it difficult find identify biomarkers which development PTSD. In this review, we summarize results recent studies regard putative PTSD suggest future research directions for biomarker discovery

参考文章(94)
Seung Hwan Han, Michael J. Quon, Jeong-a Kim, Kwang Kon Koh, Adiponectin and Cardiovascular Disease Journal of the American College of Cardiology. ,vol. 49, pp. 531- 538 ,(2007) , 10.1016/J.JACC.2006.08.061
Alexander C McFarlane, Dan J Stein, Edna B Foa, Symptomatology and psychopathology of mental health problems after disaster The Journal of Clinical Psychiatry. ,vol. 67, pp. 15- 25 ,(2006)
L Zhang, H Li, X Hu, D M Benedek, C S Fullerton, R D Forsten, J A Naifeh, X Li, H Wu, K N Benevides, T Le, S Smerin, D W Russell, R J Ursano, Mitochondria-focused gene expression profile reveals common pathways and CPT1B dysregulation in both rodent stress model and human subjects with PTSD Translational Psychiatry. ,vol. 5, ,(2015) , 10.1038/TP.2015.65
Boldizsár Czéh, Paul J. Lucassen, What causes the hippocampal volume decrease in depression? Are neurogenesis, glial changes and apoptosis implicated? European Archives of Psychiatry and Clinical Neuroscience. ,vol. 257, pp. 250- 260 ,(2007) , 10.1007/S00406-007-0728-0
Claire M. Steppan, Shannon T. Bailey, Savitha Bhat, Elizabeth J. Brown, Ronadip R. Banerjee, Christopher M. Wright, Hiralben R. Patel, Rexford S. Ahima, Mitchell A. Lazar, The hormone resistin links obesity to diabetes Nature. ,vol. 409, pp. 307- 312 ,(2001) , 10.1038/35053000
Michael J. Telch, Christopher G. Beevers, David Rosenfield, Han-Joo Lee, Albert Reijntjes, Robert E. Ferrell, Ahmad R. Hariri, 5‐HTTLPR genotype potentiates the effects of war zone stressors on the emergence of PTSD, depressive and anxiety symptoms in soldiers deployed to iraq World Psychiatry. ,vol. 14, pp. 198- 206 ,(2015) , 10.1002/WPS.20215
Robert H. Pietrzak, Jennifer A. Sumner, Allison E. Aiello, Monica Uddin, Alexander Neumeister, Guia Guffanti, Karestan C. Koenen, Association of the rs2242446 polymorphism in the norepinephrine transporter gene SLC6A2 and anxious arousal symptoms of posttraumatic stress disorder The Journal of Clinical Psychiatry. ,vol. 76, pp. 537- 538 ,(2015) , 10.4088/JCP.14L09346
Yi-lang Tang, Wenbiao Li, Kristina Mercer, Bekh Bradley, Charles F Gillespie, Robert Bonsall, Kerry J Ressler, Joseph F Cubells, None, Genotype-controlled analysis of serum dopamine β-hydroxylase activity in civilian Post-traumatic Stress Disorder Progress in Neuro-psychopharmacology & Biological Psychiatry. ,vol. 34, pp. 1396- 1401 ,(2010) , 10.1016/J.PNPBP.2010.07.002