Development of gold nanoclusters based direct fluorescence restoration approach for sensitive and selective detection of pesticide

摘要: Pesticide contamination of drinking water is high concern due to their hazardous effects on ecosystems. Several detection methods are available which associated with many drawbacks, e.g. slow response time and laborious procedural techniques. This limits practicability. Therefore, there a dire need develop quick, simpler but equally sensitive practical for pesticide detection. Herein, we report highly assay using fluorescent AuNCs the i.e., 2-methyl-4-chlorophenoxyacetic acid (MCPA). For this purpose, three different Au nanoclusters stabilized by histidine (His-AuNCs), lysozyme (Lys-AuNCs) RNase (RNase-AuNCs) were systematically studied as optical probes MCPA turn-on assay. The fluorescence these was initially quenched Cu2+ ions followed quantitative recovery signals in presence MCPA. sensitivity selectivity clusters linear dynamic range, 110–180 nM, 100–170 nM 90–160 nM case His-AuNCs, Lys-AuNCs RNase-AuNCs, respectively. Also, aforesaid having limit (LOD) each type, highest His-AuNCs (21.87), intermediate (12.97) lowest RNase-AuNCs (9.26 nM). Hence, found be most sensitive, whereas least These findings offer rapid, selective have potential implications on-site, real-time monitoring noxious pollutants.