Prospective evaluation of early treatment outcome in patients with meningiomas treated with particle therapy based on target volume definition with MRI and 68Ga-DOTATOC-PET
作者： Stephanie E. Combs , Thomas Welzel , Daniel Habermehl , Stefan Rieken , Jan-Oliver Dittmar
DOI: 10.3109/0284186X.2013.762996
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摘要: AbstractPurpose. To evaluate early treatment results and toxicity in patients with meningiomas treated particle therapy. Material methods. Seventy were protons (n = 38) or carbon ion radiotherapy 26). Median age was 49 years. at 55 years, 24 male (34%), 46 female (66%). Histology benign meningioma 26 (37%), atypical 23 (33%) anaplastic four (6%). In 17 (24%) skull base diagnosis based on the typical appearance of a meningioma. For meningiomas, total doses 52.2–57.6 GyE applied protons. high-grade lesions, boost volume 18 ions, median dose 50 as highly conformal radiation Nineteen re-irradiation. Treatment planning MRI 68-Ga-DOTATOC-PET evaluated. Results. Very low rates side effects developed, including headaches, nausea dizz...
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