Comparison of Positron Emission Tomography Scanning and Sentinel Node Biopsy in the Detection of Inguinal Node Metastases in Patients With Anal Cancer
作者： Massimiliano Mistrangelo , Ettore Pelosi , Marilena Bellò , Isabella Castellano , Paola Cassoni
DOI: 10.1016/J.IJROBP.2009.04.020
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摘要: Background Inguinal lymph node metastases in patients with anal cancer are an independent prognostic factor for local failure and overall mortality. status can be adequately assessed sentinel biopsy, the radiotherapy strategy subsequently changed. We compared this technique vs. dedicated 18F-fluorodeoxyglucose positron emission tomography (PET) to determine which was better tool staging inguinal nodes. Methods Materials In our department, 27 (9 men 18 women) underwent both biopsy PET-CT. PET-CT performed before treatment then at 1 3 months after treatment. Results scans detected no 20 of remaining 7. Histologic analysis only three (four false positives). HIV not found influence results. None negative developed during follow-up period. had a sensitivity 100%, predictive value 100%. Owing high number positives, specificity 83%, positive 43%. Conclusions series cancer, superior
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sci-hub.se 参考文章(22)
Jean-Pierre Gerard, Olivier Chapet, Farad Samiei, Eric Morignat, Sylvie Isaac, Christian Paulin, Pascale Romestaing, Véronique Favrel, Françoise Mornex, Jean-Yves Bobin, Management of inguinal lymph node metastases in patients with carcinoma of the anal canal: experience in a series of 270 patients treated in Lyon and review of the literature. Cancer. ,vol. 92, pp. 77- 84 ,(2001) , 10.1002/1097-0142(20010701)92:1<77::AID-CNCR1294>3.0.CO;2-P
H Bartelink, F Roelofsen, F Eschwege, P Rougier, J F Bosset, D G Gonzalez, D Peiffert, M van Glabbeke, M Pierart, Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups. Journal of Clinical Oncology. ,vol. 15, pp. 2040- 2049 ,(1997) , 10.1200/JCO.1997.15.5.2040
Marc C Swan, Dominic Furniss, Oliver C S Cassell, Surgical management of metastatic inguinal lymphadenopathy BMJ. ,vol. 329, pp. 1272- 1276 ,(2004) , 10.1136/BMJ.329.7477.1272
Thomas G. Trautmann, James H. Zuger, Positron Emission Tomography for Pretreatment Staging and Posttreatment Evaluation in Cancer of the Anal Canal Molecular Imaging and Biology. ,vol. 7, pp. 309- 313 ,(2005) , 10.1007/S11307-005-0003-6
Brandon T. Nguyen, Daryl Lim Joon, Vincent Khoo, George Quong, Michael Chao, Morikatsu Wada, Michael Lim Joon, Andrew See, Malcolm Feigen, Kym Rykers, Cynleen Kai, Eddy Zupan, Andrew Scott, Assessing the impact of FDG-PET in the management of anal cancer. Radiotherapy and Oncology. ,vol. 87, pp. 376- 382 ,(2008) , 10.1016/J.RADONC.2008.04.003
Maus W. Stearns, Carlos Macher, Stephen S. Ernberg, James Dodruff, Fadi Attiyeh, Cancer of the anal canal Current Problems in Cancer. ,vol. 4, pp. 1- 44 ,(1980) , 10.1016/S0147-0272(80)80015-8
D.C. Damin, M.A. Rosito, G. Schwartsmann, Sentinel lymph node in carcinoma of the anal canal: A review Ejso. ,vol. 32, pp. 247- 252 ,(2006) , 10.1016/J.EJSO.2005.08.006
Gerald T. Golden, J.Shelton Horsley, Surgical management of epidermoid carcinoma of the anus The American Journal of Surgery. ,vol. 131, pp. 275- 280 ,(1976) , 10.1016/0002-9610(76)90115-X
Norman D. Nigro, V. K. Vaitkevicius, Basil Considine, Combined therapy for cancer of the anal canal : a preliminary report Diseases of The Colon & Rectum. ,vol. 36, pp. 709- 711 ,(1974) , 10.1007/BF02238600
A. Jemal, R. Siegel, E. Ward, Y. Hao, J. Xu, T. Murray, M. J. Thun, Cancer statistics, 2008. CA: A Cancer Journal for Clinicians. ,vol. 58, pp. 71- 96 ,(2008) , 10.3322/CA.2007.0010