Physiological Study of Anal Sphincteric Resection in an Experimental Porcine Model
作者： YUICHIRO SATO , YASUMI ARAKI , YUTAKA OGATA , KAZUO SHIROUZU
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摘要: This study was conducted to compare and evaluate the extent of anal sphincteric resection degree dysfunction in sphincter saving operations for lower rectal cancer using experimental porcine models. Each 10 Clawn miniature pigs underwent transanal intersphincteric (ISR), ISR with partial (one-quarter) external (ESR-25%), (one-half) (ESR-50%). An anorectal physiological performed before, one month, three months after surgery these groups. The maximum resting pressure (AMRP) decreased from 45.1 cmH 2 O control group 14.8, 14.3 11.1 month surgery, 15.2, 8.8 5.2 ISR, ESR-25% ESR-50% groups, respectively. squeezing (AMSP) 81.7 42.1, 40.1 41.1 Three MSP increased 78.1 68.1 respectively, but showed a significantly 39.2 compared other two ratio potential difference on electromyographic (EMG) 0.19 group, this value than 0.8 surgery. EMG almost preoperative level both redness, sore soiling around anus results indicate that models additional less quarter have little dysfunction. A human clinical trial is needed determine ESR very low cancer.
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