作者: Dilip V. Jeste , Enid Rockwell , M. Jackuelyn Harris , James B. Lohr , Jonathan Lacro
DOI: 10.1097/00019442-199902000-00010
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摘要: Elderly patients with schizophrenia and dementia agitation are frequently candidates for antipsychotic treatment. Conventional neuroleptics have relatively little effect on negative symptoms may cause considerable side effects, especially in elderly patients. The authors found a 29% cumulative annual incidence of tardive dyskinesia (TD) middle-aged outpatients treated low doses conventional neuroleptics. Newer antipsychotics less likely to extrapyramidal be associated lower risk TD. They generally effective both positive also improve some aspects cognition, but these drugs their own effects. Dosing requirements tend much than those younger adults.