A General MRI-CEST Ratiometric Approach for pH Imaging: Demonstration of in Vivo pH Mapping with Iobitridol
作者： Dario L. Longo , Phillip Zhe Sun , Lorena Consolino , Filippo C. Michelotti , Fulvio Uggeri
DOI: 10.1021/JA5059313
关键词:
摘要: … ratiometric CEST MRI imposes stringent requirements on the selection of CEST contrasts agents. In this study, a novel ratiometric pH MRI method based on the analysis of CEST effects …
harvard.edu
acs.org
sci-hub.se 参考文章(35)
Amnon Bar-Shir, Guanshu Liu, Yajie Liang, Nirbhay N. Yadav, Michael T. McMahon, Piotr Walczak, Sridhar Nimmagadda, Martin G. Pomper, Keri A. Tallman, Marc M. Greenberg, Peter C.M. van Zijl, Jeff W.M. Bulte, Assaf A. Gilad, Transforming Thymidine into a Magnetic Resonance Imaging Probe for Monitoring Gene Expression Journal of the American Chemical Society. ,vol. 135, pp. 1617- 1624 ,(2013) , 10.1021/JA312353E
Enzo Terreno, Daniela Delli Castelli, Silvio Aime, Encoding the frequency dependence in MRI contrast media: the emerging class of CEST agents. Contrast Media & Molecular Imaging. ,vol. 5, pp. 78- 98 ,(2010) , 10.1002/CMMI.369
Phillip Zhe Sun, Simplified and scalable numerical solution for describing multi-pool chemical exchange saturation transfer (CEST) MRI contrast Journal of Magnetic Resonance. ,vol. 205, pp. 235- 241 ,(2010) , 10.1016/J.JMR.2010.05.004
Michael T. McMahon, Assaf A. Gilad, Jinyuan Zhou, Phillip Z. Sun, Jeff W. M. Bulte, Peter C. M. van Zijl, Quantifying exchange rates in chemical exchange saturation transfer agents using the saturation time and saturation power dependencies of the magnetization transfer effect on the magnetic resonance imaging signal (QUEST and QUESP): Ph calibration for poly-L-lysine and a starburst dendrimer Magnetic Resonance in Medicine. ,vol. 55, pp. 836- 847 ,(2006) , 10.1002/MRM.20818
Walter Dastrù, Dario Longo, Silvio Aime, Contrast agents and mechanisms Drug Discovery Today: Technologies. ,vol. 8, pp. e109- e115 ,(2011) , 10.1016/J.DDTEC.2011.11.013
Yunkou Wu, Todd C. Soesbe, Garry E. Kiefer, Piyu Zhao, A. Dean Sherry, A responsive europium(III) chelate that provides a direct readout of pH by MRI Journal of the American Chemical Society. ,vol. 132, pp. 14002- 14003 ,(2010) , 10.1021/JA106018N
Robert J. Gillies, Paul A. Schomack, Timothy W. Secomb, Natarajan Raghunand, Causes and effects of heterogeneous perfusion in tumors. Neoplasia. ,vol. 1, pp. 197- 207 ,(1999) , 10.1038/SJ.NEO.7900037
Daniela Delli Castelli, Enzo Terreno, Silvio Aime, YbIII-HPDO3A: A Dual pH- and Temperature-Responsive CEST Agent Angewandte Chemie International Edition. ,vol. 50, pp. 1798- 1800 ,(2011) , 10.1002/ANIE.201007105
Phillip Zhe Sun, Enfeng Wang, Jerry S. Cheung, Imaging acute ischemic tissue acidosis with pH-sensitive endogenous amide proton transfer (APT) MRI--correction of tissue relaxation and concomitant RF irradiation effects toward mapping quantitative cerebral tissue pH. NeuroImage. ,vol. 60, pp. 1- 6 ,(2012) , 10.1016/J.NEUROIMAGE.2011.11.091
Abiola O. Olatunde, Sarina J. Dorazio, Joseph A. Spernyak, Janet R. Morrow, The NiCEST Approach: Nickel(II) ParaCEST MRI Contrast Agents Journal of the American Chemical Society. ,vol. 134, pp. 18503- 18505 ,(2012) , 10.1021/JA307909X