An Expedient Stereoselective Synthesis of Spirocyclopropyl Oxindoles from Indolin‐2‐One/N‐Protected Indolin‐2‐Ones and Bromonitroalkenes
作者： Suparna Roy , Kwunmin Chen
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摘要: A direct and much simpler way was developed for the diastereoselective synthesis of spiro cyclopropan-1,3′-oxindoles from indolin-2-one/N-protected indolin-2-ones bromonitroalkene. The fused restrained cyclopropanes were obtained with high diastereomeric ratios (upto >99:1) in reasonable to isolated chemical yields 94%).
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