Mitochondrial Uncoupling: A Key Controller of Biological Processes in Physiology and Diseases.
作者： Demine , Renard , Arnould
DOI: 10.3390/CELLS8080795
关键词:
摘要: Mitochondrial uncoupling can be defined as a dissociation between mitochondrial membrane potential generation and its use for mitochondria-dependent ATP synthesis. Although this process was originally considered a mitochondrial dysfunction, the identification of UCP-1 as an endogenous physiological uncoupling protein suggests that the process could be involved in many other biological processes. In this review, we first compare the mitochondrial uncoupling agents available in term of mechanistic and non …
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Paolo Bernardi, Daniele Penzo, Lech Wojtczak, Mitochondrial energy dissipation by fatty acids Vitamins & Hormones. ,vol. 65, pp. 97- 126 ,(2002) , 10.1016/S0083-6729(02)65061-7
Sonya K. A. Juthberg, Tom Brismar, Effect of Metabolic Inhibitors on Membrane Potential and Ion Conductance of Rat Astrocytes Cellular and Molecular Neurobiology. ,vol. 17, pp. 367- 377 ,(1997) , 10.1023/A:1026331226241
Irina G. Shabalina, Anastasia V. Kalinovich, Barbara Cannon, Jan Nedergaard, Metabolically inert perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria Archives of Toxicology. ,vol. 90, pp. 1117- 1128 ,(2016) , 10.1007/S00204-015-1535-4
V. P. Romaschenko, R. A. Zinovkin, I. I. Galkin, V. V. Zakharova, A. A. Panteleeva, A. V. Tokarchuk, K. G. Lyamzaev, O. Yu. Pletjushkina, B. V. Chernyak, E. N. Popova, Low concentrations of uncouplers of oxidative phosphorylation prevent inflammatory activation of endothelial cells by tumor necrosis factor Biochemistry (Moscow). ,vol. 80, pp. 610- 619 ,(2015) , 10.1134/S0006297915050144
Jing Ma, Chaemin Lim, Joshua R. Sacher, Bennett Van Houten, Wei Qian, Peter Wipf, Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells Bioorganic & Medicinal Chemistry Letters. ,vol. 25, pp. 4828- 4833 ,(2015) , 10.1016/J.BMCL.2015.06.073
Patrycja Kaczara, Roberto Motterlini, Gerald M. Rosen, Bartlomiej Augustynek, Piotr Bednarczyk, Adam Szewczyk, Roberta Foresti, Stefan Chlopicki, Carbon monoxide released by CORM-401 uncouples mitochondrial respiration and inhibits glycolysis in endothelial cells: A role for mitoBKCa channels. Biochimica et Biophysica Acta. ,vol. 1847, pp. 1297- 1309 ,(2015) , 10.1016/J.BBABIO.2015.07.004
Jeong Su Park, Dong Hoon Kang, Soo Han Bae, p62 prevents carbonyl cyanide m-chlorophenyl hydrazine (CCCP)-induced apoptotic cell death by activating Nrf2. Biochemical and Biophysical Research Communications. ,vol. 464, pp. 1139- 1144 ,(2015) , 10.1016/J.BBRC.2015.07.093
Dieter A. Kubli, Melissa Q. Cortez, Alexandra G. Moyzis, Rita H. Najor, Youngil Lee, Åsa B. Gustafsson, PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes PLOS ONE. ,vol. 10, pp. e0130707- ,(2015) , 10.1371/JOURNAL.PONE.0130707
L.J. Bukowiecki, N Folléa, J Lupien, A Paradis, Metabolic relationships between lipolysis and respiration in rat brown adipocytes. The role of long chain fatty acids as regulators of mitochondrial respiration and feedback inhibitors of lipolysis. Journal of Biological Chemistry. ,vol. 256, pp. 12840- 12848 ,(1981) , 10.1016/S0021-9258(18)42972-9
S Rehnmark, M Néchad, D Herron, B Cannon, J Nedergaard, Alpha- and beta-adrenergic induction of the expression of the uncoupling protein thermogenin in brown adipocytes differentiated in culture. Journal of Biological Chemistry. ,vol. 265, pp. 16464- 16471 ,(1990) , 10.1016/S0021-9258(17)46245-4