Comparison of Hydrogels Based on Commercial Chitosan and Beetosan(®) Containing Nanosilver.

作者: Bożena Tyliszczak , Anna Drabczyk , Sonia Kudłacik

DOI: 10.3390/MOLECULES22010061

关键词:

摘要: Two series of hydrogels on the basis commercial chitosan and derived from naturally expired honeybees are presented in this article. Sorption capacity behavior both kind materials simulated body fluids such as Ringer’s liquid or artificial saliva have been determined compared. Presence functional groups synthesized by means FT-IR spectroscopy. Structure homogeneity their surface defined using Scanning Electron Microscopy. Based conducted research, it can be stated that Beetosan® very similar characteristics. It is worth noting synthesis environmentally friendly leads to obtaining polymers used for biomedical applications. Tested characterized low sorption do not a negative impact fluids. Moreover, based cell lines studies, influence cells cancerous origin and, what important, significantly less adverse effects fibroblasts.

参考文章(17)
Federica Bigucci, Angela Abruzzo, Bruno Saladini, Maria Caterina Gallucci, Teresa Cerchiara, Barbara Luppi, Development and characterization of chitosan/hyaluronan film for transdermal delivery of thiocolchicoside. Carbohydrate Polymers. ,vol. 130, pp. 32- 40 ,(2015) , 10.1016/J.CARBPOL.2015.04.067
Angela Abruzzo, Teresa Cerchiara, Federica Bigucci, Maria Caterina Gallucci, Barbara Luppi, Mucoadhesive Buccal Tablets Based on Chitosan/Gelatin Microparticles for Delivery of Propranolol Hydrochloride. Journal of Pharmaceutical Sciences. ,vol. 104, pp. 4365- 4372 ,(2015) , 10.1002/JPS.24688
Bożena Tyliszczak, Krzysztof Pielichowski, Novel hydrogels containing nanosilver for biomedical applications - synthesis and characterization Journal of Polymer Research. ,vol. 20, pp. 191- ,(2013) , 10.1007/S10965-013-0191-8
S. V. Nemtsev, O. Yu. Zueva, M. R. Khismatullin, A. I. Albulov, V. P. Varlamov, Isolation of Chitin and Chitosan from Honeybees Applied Biochemistry and Microbiology. ,vol. 40, pp. 39- 43 ,(2004) , 10.1023/B:ABIM.0000010349.62620.49
Zbigniew Draczynski, Honeybee corpses as an available source of chitin Journal of Applied Polymer Science. ,vol. 109, pp. 1974- 1981 ,(2008) , 10.1002/APP.28356
Marja N Storm-Versloot, Cornelis G Vos, Dirk T Ubbink, Hester Vermeulen, Topical silver for preventing wound infection Cochrane Database of Systematic Reviews. ,vol. 2010, ,(2010) , 10.1002/14651858.CD006478.PUB2
Jinhua Liu, Yongxing Zhao, Qianqian Guo, Zhao Wang, Huiyuan Wang, Yongxin Yang, Yongzhuo Huang, TAT-modified nanosilver for combating multidrug-resistant cancer. Biomaterials. ,vol. 33, pp. 6155- 6161 ,(2012) , 10.1016/J.BIOMATERIALS.2012.05.035
Christina Greulich, Dieter Braun, Alexander Peetsch, Jörg Diendorf, Bettina Siebers, Matthias Epple, Manfred Köller, The toxic effect of silver ions and silver nanoparticles towards bacteria and human cells occurs in the same concentration range RSC Advances. ,vol. 2, pp. 6981- 6987 ,(2012) , 10.1039/C2RA20684F
J.L. Castro-Mayorga, M.J. Fabra, J.M. Lagaron, Stabilized nanosilver based antimicrobial poly(3-hydroxybutyrate-co-3-hydroxyvalerate) nanocomposites of interest in active food packaging Innovative Food Science and Emerging Technologies. ,vol. 33, pp. 524- 533 ,(2016) , 10.1016/J.IFSET.2015.10.019
T. Cerchiara, A. Abruzzo, C. Parolin, B. Vitali, F. Bigucci, M.C. Gallucci, F.P. Nicoletta, B. Luppi, Microparticles based on chitosan/carboxymethylcellulose polyelectrolyte complexes for colon delivery of vancomycin Carbohydrate Polymers. ,vol. 143, pp. 124- 130 ,(2016) , 10.1016/J.CARBPOL.2016.02.020